WEB107 Bioburden-Biofilms in Inflammation
Released Apr 27, 2017
Expires Apr 27, 2019
Bioburden-Biofilms in Inflammation
Webinar 4 of 6 in the Inflammation and Wound Chronicity series.
Bacterial biofilms are known to play major roles in multiple diseases that are characterized by chronic inflammation and tissue breakdown, such as osteomyelitis, cystic fibrosis, chronic sinusitis, and catheter infections. Recent data have established that >80% of chronic skin wounds have bacterial biofilms that contribute to the chronic inflammation state and resulting elevated levels of proteases (MMPs and elastase) and reactive oxygen species (ROS) that destroy proteins that are essential for healing. Biofilm based wound care emphasizes the importance of “step down therapy” that starts with treatments that most effectively debride biofilms and combined with treatments that kill residual biofilms and prevent new biofilms from forming. As inflammation is reduced and protease levels decrease, treatments are shifted to advanced agents that actively promote healing such as growth factors, dermal matrix dressings, biologically active membrane dressings and skin grafts.
Physicians, PAs, NPs, Nurses, Discharge Planners, Admissions Coordinators, Social Services.
Learning ObjectivesUpon completion of program:
- Identify the phases of wound healing and the mechanisms of inflammation.
- Recognize the wound which has stalled in healing due to excessive inflammation.
- Describe clinical strategies to treat excessive inflammation.
- Demonstrate that implementation of appropriate management algorithms improves patient healing and clinical outcomes.
- Demonstrate team based communication that will foster implementation of appropriate management algorithms resulting in improved patient healing and clinical outcomes.
Dr. Schultz is Professor of Obstetrics & Gynecology and Director of the Institute for Wound Research at the University of Florida. Dr. Schultz completed a PhD in Biochemistry from Oklahoma State University and Postdoctoral training in Cell Biology at Yale University. Dr. Schultz's research focuses on the molecular regulation of wound healing, with an emphasis on anti-scarring therapies and the roles of elevated proteases and bacterial biofilms in chronic wounds. Dr. Schultz has authored over 325 scientific publications that have been cited more than 14,000 times with an h-index of 61, is PI or Co-investigator on grants totaling over $35 million, is an inventor on 27 patents and a co-founder of two biotech companies. He was recognized by TIME magazine as an Innovation Leader in 2006. He served as a member of the National Pressure Ulcer Advisory Panel from 2007-2010, and served as President of the Wound Healing Society from 1999-2001 and was elected a Silver Fellow of Association for Research in Vision and Ophthalmology in 2010.
Gregory Schultz, PhD has no relevant financial relationship to disclose.
Ruchit Parikh, PharmD
Associate Medical Director
Haymarket Medical Education
Dr. Parikh has no relevant financial relationships to disclose
Accredited Provider Disclosure
Haymarket Medical Education staff involved in the planning and content review of this activity have no relevant financial relationships to disclose.
Haymarket Medical Education is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Haymarket Medical Education designates this enduring material for a maximum of 1.0 AMA PRA Category 1 CreditTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Disclosure of Unlabeled Use
This CME activity may or may not discuss investigational, unapproved, or off-label use of drugs. Participants are advised to consult prescribing information for any products discussed. The information provided in this CME activity is for continuing medical education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options for a specific patient’s medical condition.
The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of Haymarket Medical Education and Acelity. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
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To obtain credit, a score of 70% or better on the post-test is required. This activity is offered at no cost to participants. Please proceed with the activity until you have successfully completed this program, answered all test questions, completed the post-test and evaluation, and have received a copy of your credit certificate.